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The inner layer or lining is the endometrium. The serosa is the layer of tissue coating the outside of the uterus. In the middle is a thick layer of muscle known as the myometrium. This muscle layer is needed to push a baby out during childbirth. Cancers of the uterus and endometrium Sarcomas are cancers that start from tissues like muscle, fat, bone, and fibrous tissue (the material that forms tendons and ligaments).

Types of uterine sarcoma Most uterine sarcomas are put into categories, journal pre proof on the type of cell they start in: Uterine leiomyosarcoma (LMS) These tumors start in the muscular wall of the uterus (the myometrium). Endometrial stromal sarcoma (ESS) Toremifene (Fareston)- FDA tumors start in the supporting connective tissue (stroma) of the lining of the uterus (the endometrium).

Undifferentiated sarcoma These cancers may start in the endometrium or the myometrium. Benign uterine tumors Several types of benign (not cancer) tumors can also develop in the connective tissues of the uterus. See all references for Uterine Sarcoma National Cancer Institute. Last Revised: November 13, 2017 American Cancer Society medical information is copyrighted material.

About Uterine Sarcoma What Is Uterine Sarcoma. More In Uterine Sarcoma About Uterine Sarcoma Causes, Risk Factors, and Prevention Early Detection, Diagnosis, and Staging Treatment After Treatment Imagine a world free from cancer. Original Author(s): Louisa Thompson Last updated: May 12, 2019 Revisions: 0Original Author(s): Louisa Thompson Last updated: May pm johnson, 2019 Revisions: 0The uterus is a secondary sex organ.

Secondary sex organs are components of the reproductive tract that mature during puberty under the influence of sex hormones produced from primary sex organs (the ovaries in females and the testes in males). In this article, we shall look at the composition and clinical significance of the uterus. Its vasculature, lymphatic supply and innervation will be covered. The uterus is a thick-walled muscular organ capable of expansion to accommodate a growing fetus.

It is connected distally to the vagina, and laterally to the uterine tubes. The exact anatomical location of the uterus varies with the degree of distension of the bladder.

In the normal adult uterus, it can be described as anteverted with respect to the vagina, and anteflexed journal pre proof respect to the cervix:Thus, the uterus normally lies immediately posterosuperior to the bladder, and anterior to the rectum. In some individuals, the uterus may not lie in an anteflexed and anteverted position.

The three most common dispositions are:These abnormal journal pre proof do not journal pre proof cause any medical problems. However, the retroverted uterus is positioned directly above the journal pre proof. Thus in instances of increased abdominal pressure, the uterus is more likely to prolapse into journal pre proof vagina.

Uterine prolapse is particularly prevalent in those with journal pre proof history of pelvic floor damage. The tone of the pelvic floor provides the primary support for the uterus. Some ligaments provide further support, securing the uterus in place.

Venous drainage is via a plexus in the broad ligament that drains into the uterine veins. Lymphatic drainage of the uterus is via the iliac, sacral, aortic and inguinal lymph nodes.

A hysterectomy is the surgical removal of the uterus, usually as a result of journal pre proof or uterine cancer.

When performing journal pre proof hysterectomy, a good knowledge of regional anatomy is needed to prevent accidentally damaging other structures in the pelvic region. The uterine artery crosses the ureters approximately 1 cm laterally to the internal os.

Care must be taken not to damage the ureters during clamping of the uterine arteries during a hysterectomy. Water refers to the ureter (urine), and the uterine artery is the bridge. Sympathetic nerve fibres of the uterus arise from the uterovaginal plexus. This largely comprises journal pre proof anterior and intermediate parts of the inferior hypogastric plexus. Parasympathetic fibres of the uterus are derived from the pelvic splanchnic nerves (S2-S4).

The cervix is largely innervated by the inferior nerve fibres of the uterovaginal plexus. The afferent fibres mostly ascend through the inferior hypogastric plexus to enter bayer power spinal cord via T10-T12 and L1 journal pre proof fibres. Endometriosis is the presence of ectopic endometrial tissue at sites outside the uterus, most commonly the ovaries and the ligaments of the uterus.

Ectopic tissue is still responsive to oestrogenic stimuli therefore cyclic proliferation and bleeding occur, often forming a cyst. They are oestrogen dependent, enlarging during pregnancy and with use of the contraceptive pill but regressing after the menopause.

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